Aldama and the Grizzlies had a strong third quarter to turn the game into a blowout. Aldama eclipsed his previous career high of 28 points in the fourth quarter. Edey took a shot to the face in the first half and was later ruled out with a nose injury.

The Grizzlies beat the Spurs on Wednesday night at the Frost Bank Center, and they'll meet again on Friday night. San Antonio (19-20) will be looking for revenge after Wednesday's loss, while Memphis (26-15) is looking to finish off the four-game road trip with a win.

The Grizzlies and Spurs meet for the second time this week on the heels of a double digit Memphis win on Wednesday night.  In what could be a postseason preview

The Spurs will be in front of their home fans on Friday, but a look at the spread shows they might need that home-court advantage. They will host the Memphis Grizzlies at 9:30 p.m. ET at Frost Bank Center.

SAN ANTONIO — Memphis Grizzlies star Ja Morant is unlikely to play against the San Antonio Spurs on Friday, Grizzlies coach Taylor Jenkins said.

Santi Aldama scored a career-high 29 points and the Memphis Grizzlies rolled to a 140-112 victory over San Antonio on Friday night, handing the Spurs their largest losing margin of the season even with Ja Morant sidelined by a foot injury.