49ers, Week 3 and New Orleans Saints
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The Arizona Cardinals will open the season this weekend on the road against the New Orleans Saints. They kick off from Caesars Superdome Sunday at 1 p.m. ET (10 a.m. Arizona time). They hope to do something they have not done this century — beat the Saints on the road.
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6 days until Saints season opener: Every player to wear No. 6
Tyler Shough was the 40th overall choice in the 2025 NFL draft from the Louisville Cardinals. He will be the highest-drafted Saint to wear No. 6 to date and the highest-drafted quarterback by the team since Archie Manning in 1971.
The Arizona Cardinals open their season at the New Orleans Saints. As 6.5-point favorites, it's crucial that they pick up a Week 1 road victory.