Just two games into the season, the Rams (0-2) are approaching desperate times as they prepare to face the San Francisco 49ers (1-1) Sunday afternoon at SoFi Stadium. The list of issues thus far for the Rams is probably as long as their injury report.

Two key Rams players are improving ahead of Sunday’s game, while the 49ers added three starters to the injury report on Thursday. Notably, Cobie Durant and Kevin Dotson are making progress;

If Kittle does miss Sunday's game, he will join star running back Christian McCaffrey, who is currently on the Injured Reserve list with a calf injury and Achilles tendonitis. Wide receiver Deebo Samuel is also missing time following a calf injury he suffered in Week 2. Quarterback Brock Purdy is running low on targets to throw to.

Adding to the complications, cornerback Charvarius Ward also missed practice, struggling with both a hamstring and a knee injury. Meanwhile, safety Talanoa Hufanga is nearing a return from ACL surgery, but the 49ers may have to rely on younger, less experienced players to fill critical roles during this tough stretch.

The Los Angeles Rams host the San Francisco 49ers on Sunday as both NFC West rivals try to shake off dismal Week 2 performances.

The Rams have their work cut out for them in Week 3 but they have a chance to upset the 49ers if they win these 5 matchups

The San Francisco 49ers (1-1) visit the Los Angeles Rams (0-2) on Sunday, September 22, 2024 in matchup between NFC West rivals at SoFi Stadium. The Rams are listed as 6.5-point underdogs. For

Although the famed Rams-49ers rivalry has been decidedly tilted in San Francisco’s direction in recent years, the games have still been must-see spectacles.

See who's in and who's out for the Week 3 matchup between the San Francisco 49ers and Los Angeles Rams on September 22, 2024.

The San Francisco 49ers have been bit by the injury bug early in the 2024 season, and another superstar popped up on the injury report on Thursday.