AbstractNoncanonical metabolic functions of signaling molecules contribute to cancer plasticity and metastatic progression. In this study, we demonstrated that phosphodiesterase type 5A (PDE5A) ...
Abstract. Colorectal cancer is the second leading cause of cancer deaths in the United States, with a 5-year survival rate of 65%. Oxaliplatin was the first platinum (Pt) drug shown to improve ...
AbstractDeveloping chimeric antigen receptor (CAR) T cells for acute myeloid leukemia (AML) has been challenging due to a lack of known AML-associated antigens that spare normal hematopoietic ...
Abstract. Antibody-drug conjugates (ADCs) show clinical efficacy against several solid malignancies, inducing cytotoxic effects in malignant cells accompanied by changes in the composition of the ...
Abstract. Cancer-associated fibroblasts (CAFs) drive key aspects of tumor malignancy. However, the profound heterogeneity in cytokine secretion and cell-cell communication orchestrated by CAFs renders ...
Cancer Discov (2026) 16 (8): OF1.
Cancer Discov (2026) 16 (8): OF1.
Cancer Discov (2026) 16 (8): OF1.
Cancer Discov (2026) 16 (8): OF1.
Cancer Discov (2026) 16 (8): OF1.
Cancer Discov (2026) 16 (8): OF1.
AbstractThe disease burden from non–small cell lung cancer (NSCLC) adenocarcinoma is substantial, with a million new cases diagnosed globally each year and a 5-year survival rate of less than 20%. The ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results