AbstractThe disease burden from non–small cell lung cancer (NSCLC) adenocarcinoma is substantial, with a million new cases diagnosed globally each year and a 5-year survival rate of less than 20%. The ...
Abstract. Cancer-associated fibroblasts (CAFs) drive key aspects of tumor malignancy. However, the profound heterogeneity in cytokine secretion and cell-cell communication orchestrated by CAFs renders ...
Abstract. KRAS mutations, present in about 40% of colorectal cancers (CRCs), are strongly associated with an immunosuppressive tumor microenvironment characterized by restricted immune infiltration ...
2Department of Medicine, Keck School of Medicine of USC, Los Angeles, California. 3UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Cancer Discov (2026) 16 (8): OF1.