"There remains a tremendous unmet need in myelofibrosis, as less than half of patients achieve ... success of our Phase 3 SENTRY trial increases based on the change in the co-primary endpoint to ...

Karyopharm intends to enroll approximately 350 JAKi naïve patients with myelofibrosis in this Phase 3 trial; patients are randomized 2-to-1 to the selinexor arm. The co-primary endpoints will be ...

Promising Improvement in Abs-TSS and SVR35 from Phase 1 Trial of Selinexor in Combination with Ruxolitinib Adds Confidence in Phase 3 SENTRY Trial Proactively Increasing Total Sample Size of the ...

"There remains a tremendous unmet need in myelofibrosis, as less than half ... 3 SENTRY trial increases based on the change in the co-primary endpoint to Abs-TSS, the increased sample size and ...

Inrebic showed superior spleen volume reduction and symptom response compared to BAT in myelofibrosis patients previously treated with Jakafi. The FREEDOM2 trial involved 134 patients treated with ...

Co-primary Endpoint Changed to Absolute Total Symptom Score (Abs-TSS) from Total Symptom Score Improvement of ≥ 50% (TSS50) Following Alignment with the FDA Karyopharm Announces Favorable Change in Co ...

What is staphylococcal scalded skin syndrome in children? Staphylococcal scalded skin syndrome (SSSS) is a serious skin infection. The infection causes peeling skin over large parts of the body. It ...

A new study published in the Journal of Drug and Dermatology found that any person with primary hyperhidrosis is more likely than the general population to have sensitive skin even in places where ...

Trying to achieve healthier skin? Follow these quick tips from board-certified dermatologists to learn healthy skin habits. For even more recommendations on maintaining healthy skin, see the list ...

Crafting a diligent and effective skin routine is not at all easy, and requires years of research and a long journey of trial and error that often comes with a hefty ...