A new study by Kos and colleagues suggests that the glycoprotein SPARC limits adipose-tissue expansion and promotes inflammation and insulin resistance. ...expression of SPARC positively ...

“When things affect fat, it affects our entire body.” Body fat, or adipose tissue, is a complex organ. It contains fat cells, nerves, immune cells, and connective tissue. Its main job is to ...

"If we think about white adipose tissue expansion, then what are the mediators of this? And then, can we target these mediators to have beneficial effects, and maybe these targets are going to be ...

The findings offer promising support for progressing ADPO-002NP treatment to first-in-human Phase I clinical trials. Adipo ...

If we think about white adipose tissue expansion, then what are the mediators of this? And then, can we target these mediators to have beneficial effects, and maybe these targets are going to be ...

Department of Physiology, Harold Hamm Diabetes Center, The University of Oklahoma Health Science Center, Oklahoma City, United States ...

A defined, serum-free and xeno-free culture system optimized for the growth and expansion of hMSCs from a variety of sources: placenta (hMSC-PL), adipose-tissue (hMSC-AT), Wharton jelly (hMSC-WJ) and ...

Adipo Therapeutics LLC, a late-stage, preclinical biopharmaceutical company developing a potential treatment for obesity and ...

The Mohammad Lab is interested in studying the effects of dietary fatty acids of varying carbon chain length (short, medium, and long) on adipose tissue expansion, the development of obesity, and ...

The study found that microplastic particles (MPs) not only induce senescence in white adipose tissue but also significantly impair adipogenesis, reducing lipid droplet formation in both white and ...