The San Francisco 49ers will take on the Buffalo Bills in the Week 13 edition of NBC's "Sunday Night Football." What to know about the game.

Fresh from their bye week, the Bills (9-2) will host the 49ers (5-6) at Highmark Stadium for an NFL Week 13 clash on Sunday. Buffalo defeated the Chiefs 30-21 in their previous match to extend their winning streak to six. Yet to lose a game at home, the ...

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The Tennessee Titans fell to the San Francisco 49ers in Week 15 action, and here is how Titans Wire graded the team's performance.