If you buy something through a link in this article, we may earn commission. Pricing and availability are subject to change. There are a number of really interesting NFL matchups taking place this weekend, including Giants vs. 49ers. The New York Giants ...

SANTA CLARA --This is the San Francisco 49ers live blog for Day 1 of the NFL Draft. I will update this frequently with information and analysis from the Levi's Stadium media room. 4:30 The 49ers currently do not own a pick in Round 1 -- they traded it to ...

The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the team’s fourth win in a row.

The San Francisco 49ers are heading east for a matchup with the Tampa Bay Buccaneers that’ll pit two NFC division leaders with identical 4-1 records against each other. The 49ers last played under a Thursday night spotlight in Week 5; despite being one ...

The 49ers are 12.5-point favorites, per the latest Titans vs. 49ers odds, and the over/under for total points scored is 44.5 at DraftKings. The 49ers are -901 money line favorites (risk $901 to win $100),

A playoff spot is within reach for the San Francisco 49ers if they take care of business vs. the Tennessee Titans on Sunday.