The Israel Defense Forces (IDF) said the Damascus headquarters served as a command center for deploying regime forces to Suwayda, a southern Syrian region gripped by days of deadly clashes between government troops, Druze militias, and Bedouin groups.

The Israeli military launched airstrikes in the heart of Damascus on Wednesday, hitting the Syrian Defense Ministry headquarters.

The Syrian Observatory for Human Rights, a U.K.-based war monitor, said the clashes started after members of a Bedouin tribe in Sweida province set up a checkpoint where they attacked and robbed a Druze man, leading to tit-for-tat attacks and kidnappings between the tribes and Druze armed groups.

A series of airstrikes has hit the Syrian capital Damascus, with Syrian state media blaming Israel. One video from a Syrian television channel shows the Ministry of Defense building being hit live on air, forcing the anchor to take cover. Israel’s Defense Minister Israel Katz shared the footage, saying “the painful blows have begun.”

The dayslong fighting has threatened to unravel Syria’s postwar political transition and brought in further military intervention by Israel.

Syria completely reopened its airspace on June 24, its civil air authority said. Damascus Airport's two runways were damaged during the civil war but have since been repaired. The airport was also looted during the chaos of Assad's fall.

Open-source intelligence analysts reported that a mass mobilization was declared in all of Syria's governorates despite the ceasefire.